Activiteit

Likely perturbations of host cellular metal homeostasis by SARS-CoV-2 infection are highlighted.

The number of people above the age of 60 years is raising world-wide being associated with an increase in the prevalence of aging-associated impairments and even diseases. Recent studies suggest that aging is associated with alterations in bacterial endotoxin levels and that these changes may add to low-grade inflammation, the so-called ‘inflammaging’, and aging-associated liver degeneration. However, mechanisms involved, and especially, the interaction of intestinal microbiota and barrier in the development of aging-associated inflammation and liver degeneration have not been fully understood.

The aim of the present study was to determine if intestinal microbiota composition changes with age and if these alterations are associated with changes of markers of intestinal barrier function and the development of inflammation and liver degeneration.

Blood, liver, small and large intestinal tissue of male 2-, 15-, 24- and 30-months old C57BL/6 mice fed standard chow were obtained. Intestinal microbiota compos and increase with age.

Substantial public health measures occurred in Australian society during the COVID-19 pandemic to reduce the risk of community transmission. Little was known about the impact of these changes on childbearing women.

To describe childbearing women’s experiences of becoming a mother during the COVID-19 pandemic in Australia.

A qualitative exploratory design using semi-structured interviews was used. Women were recruited through social media and self-nominated to participate in an interview. Maximum variation sampling was used. A total of 27 interviews were conducted with women across Australia. Data were analysed thematically.

The thematic analysis resulted in four primary themes and ten sub-themes. The themes were ‘going it alone – having a baby was an isolating experience’ (‘receiving maternity care alone’, ‘dealing with government restrictions’, and ‘desiring social support’), ‘advocating for self or others’ (‘seeking reliable information’, ‘valuing peersupport’, and ‘having to be resourceful’), ‘findatives are implemented to keep people safe, the social and emotional toll on childbearing women should be considered by healthcare professionals. Childbearing women need to be safe but also require support and reassurance.

In 2018, 17 percent of all births in the United States occurred to women of advanced maternal age (AMA.) While the outcomes of AMA pregnancies have been examined extensively, the drivers behind increasing rates of AMA pregnancies in the United States are less understood. Some scholars have asserted that women are increasingly delaying their first birth in favor of educational and career aspirations. Yet birth trends in the United States do not support this as the primary explanatory factor of AMA births. Other factors may also contribute to high rates of AMA in the United States. This study sought to identify main predictors of AMA birth using a cross-sectional retrospective sample.

We employed a multivariate logistic regression analysis on a cross-sectional retrospective sample to identify significant independent predictors of giving birth at advance maternal age (AMA) in the United States.

Data was obtained from the Unites States Pregnancy Risk Assessment Monitoring System (PRAMS) Phase 7 Core Questiosure that women’s preferences, particularly women of color, are upheld while promoting health and wellbeing for women.The sludges derived from the leachate treatment (LS) represent an important environmental and operational problem in the landfill management. On the other hand, they can be utilized as an alternative source of nutrients and organic matter. dWIZ-2 The main objective of this work was to evaluate the reuse of the LS of a sanitary landfill in Santa Fe city – Argentina, as an organic amendment for the development of Nicotiana alata L. plants. Different doses of LS were applied to a soil mixture for potted seedling growth. The response surface methodology was applied, using a one-factor design. Once the phenological stage of flowering began, the plants were harvested. Physiological and biochemical determinations were made in order to evaluate the effects of the different amendments. Application of LS notably improved growth parameters such as stem height, leaf area and dry matter. Additionally, the content of proteins and photosynthetic pigments was enhanced. Through the multiple regression statistical analyses, the relationship between the response variables and the sludge content was established. The multivariate optimization analysis yielded 53% as the optimal sludge content. Our results indicate that this sludge, in appropriate doses, can be used as an organic amendment for the revegetation of sanitary landfills.Community-based monitoring is increasingly recognised as one solution to sustainable environmental management. However, the development of community-based monitoring has led to confusion or misconceptions regarding other similar initiatives. Through a review of the characteristics and synthesising criteria of effective community-based monitoring, this article addresses how to distinguish community-based monitoring from other forms of community engagement research. A review of relevant community-based monitoring literature identifies the characteristics of and knowledge gaps in procedures and governance structures. Additionally, evidence of common benefits, challenges and lessons learned for successful community-based monitoring are deliberated. As an outcome of the review, the article synthesises a set of community-based monitoring criteria as follows (1) efficacy of initiatives, (2) technicality aspects, (3) feedback mechanisms and (4) sustainability. These synthesised criteria will be instrumental in designing customised community-based monitoring initiatives for environmental sustainability.The much-publicized threats to coral reef systems necessitate a considered management response based on comprehensive ecological data. However, data from large reef systems commonly originate from multiple monitoring programs that use different methods, each with distinct biases that limit united assessments of ecological status. The effective integration of data from different monitoring methods would allow better assessment of system status and hence, more informed management. Here we examine the scope for comparability and complementarity of fish data from two different methods used on Australia’s Great Barrier Reef (GBR) underwater visual census (UVC) and baited remote underwater video stations (BRUVS). We compared commonly reported reef fish measures from UVC and BRUVS on similar reef slope habitats of three central GBR reefs. Both methods recorded similar estimates of total species richness, although ~30% of recorded species were not common to both methods. There were marked differences between methods in sub-group species richness, frequency of species occurrences, relative abundances of taxa and assemblage structure.