Activiteit

02). In the cost-effectiveness analysis, the cost-effectiveness threshold was $ 16,482; ICER in increasing the QoL and reduction in the mortality rate was $ 25320.11 and $ 562.6691, respectively. Regarding the sensitivity analysis, the model was not sensitive in changing parameters in a specific domain. Conclusion According to this study, PCI is more cost-effective than medical therapy in the reduction of mortality rate and in the field of increasing quality of life. MT strategy is more cost-effective than the PCI. This study considers controversies regarding the most appropriate treatment for patients with ischemic heart disease that is helpful for health policymakers, cardiologists and health managers.

Nutrition plays a pivotal role in the prevention and treatment of endocrine disorders. The aim of this study was to provide a window in order to display the 25-year activities of Endocrinology & Metabolism Research Institute (EMRI), and the gaps and future plans in the field of nutrition and endocrine disorders.

To collect papers affiliated to the EMRI in field of nutrition from the inception to December 1st 2019, the electronic databases including PubMed/Medline, Web of Science, and Scopus were searched. Publications in English and Persian languages were included. Scientific Landscapes (VOS viewer) software version 1.6.13 was used to provide bibliometric maps.

Of 4082 studies identified in the initial search, 319 relevant papers were included. They contributed systematic review and meta-analysis/review (

 = 76), clinical trials (

 = 58), cross-sectional (

 = 171), case-control studies (

 = 11), and animal studies (

 = 3). Accordingly, most nutrition studies were dedicated to the level of evideing the situations of our society can be helpful to make nutritional findings more practical.The concomitant use of various types of models (in silico, in vitro, and in vivo) has been exemplified here within the context of biomedical researches performed in the Endocrinology and Metabolism Research Institute (EMRI) of Tehran University of Medical Sciences. Two main research aeras have been discussed the search for new small molecules as therapeutics for diabetes and related metabolic conditions, and diseases related to protein aggregation. Due to their multidisciplinary nature, the majority of these studies have needed the collaboration of different specialties. In both cases, a brief overview of the subject is provided through literature examples, and sequential use of these methods is described.Non-communicable Diseases (NCDs) are the leading causes of death globally, imposing a heavy burden on the healthcare systems, especially in low- and middle-income countries. Iran is a country in the Middle-East region with an aging population and changing disease risk factors, and now is facing NCDs as the major health problem of the country. Investigating NCDs’ risk factors and tackling preventable ones is the main intervention to control their heavy burden. In this review, we discussed the most critical risk factors in Iran and the implemented programs and action plans to control them. A better knowledge on current status of risk factors and plans to tackle them, could help policymakers effectively rule policies and allocate resources to curb heavy burden of NCDs in Iran.

COVID-19 has presented the surgical community with a multitude of challenges. Patients requiring surgical intervention who are positive for COVID-19 are not only more likely to develop complications post-operatively, but also pose an increased infection risk to the surgical team involved in their care. The infection control concerns raised at the peak of the pandemic persist in the post-pandemic era as patients continue to test positive for COVID-19 and the risk of a ‘second wave’ looms.

We present a case series (compliant with SCARE [4] and PROCESS [5] criteria) to demonstrate the effective use of an AR technology platform during the intraoperative treatment of two complex COVID positive patients diagnosed with Fournier’s gangrene.Retrospective review of prospectively collected data of all patients that required surgery involving multiple specialties during the COVID-19 pandemic at Jaber AlAhmad hospital in Kuwait between March 2020 to October 2020.

We present two cases to highlight the use of an augmented reality (AR) platform during the treatment of COVID-19 positive patients with Fournier’s gangrene in order to safeguard surgical teams whilst simultaneously enabling these complex cases to benefit from multi-specialty input intraoperatively.

Augmented reality is a feasible option to minimize surgeons’ exposure during surgery without compromising the patients safety.

This case series demonstrates how AR solutions can be employed to bolster infection control measures and may be useful in the treatment of surgical patients who test positive for COVID-19.

AR solutions could be considered as an infection control strategy to safeguard surgical teams operating on COVID-19 positive patients.

AR solutions could be considered as an infection control strategy to safeguard surgical teams operating on COVID-19 positive patients.

Infectious diseases represent up to 12% of all deaths in people with diabetes mellitus (DM). The development and progression of DM generate a chronic inflammatory state with unique characteristics that have been exploited by some pathogens; one of them is

spp., a fungus considered the causative agent of mucormycosis. This disease has a poor prognosis with high mortality rates, and the apparition of resistant isolates each year has become a worrying concern. DM is an actual and continuing health problem, and for that reason, it is of foremost importance to study the pathogenesis of mucormycosis to generate new prevention and treatment strategies.

The worldwide incidence of mucormycosis has increased in recent years. Halofuginone mw The pathogenic mechanisms and factors identified in

spp. are the cell wall, spore germination, proteins, and enzymes related to iron sequestration, CotH fungal protein, positive regulation of the GRP78 cell receptor, and immune evasion due to survival within phagocytes, among others. The physiopathology of DM offers favorable conditions for the successful replication of

spp.