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actief 2 dagen, 4 uren geleden-
McCann McPherson heeft een update geplaatst 2 dagen, 4 uren geleden
Nutrient sensing metabolic pathways critically regulate stem cell maintenance during aging and in response to diet. Elucidating the molecular mechanisms underlying dietary and metabolic regulation of stem cells provides novel insights for stem cell biology and may be targeted therapeutically to reverse stem cell aging and tissue…[Lees meer]
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McCann McPherson heeft een update geplaatst 3 dagen, 5 uren geleden
5% in 2015) and was highest in Community Cancer Programs (41.2% in 2012 to 29.1% in 2015). Median number of positive SLN did not differ between groups (p = .563). Median number of nodes retrieved on ALND decreased from 9 (IQR 5-14) in 2012 to 7 (IQR 4-12) in 2015 (p less then .001). In patients who met the ACOSOG Z11 trial guidelines, rates of…[Lees meer]
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McCann McPherson heeft een update geplaatst 1 week, 1 dag geleden
No significant differences between gBRCA2 carriers and non-carriers were observed in the prevalence of IDC (36% gBRCA2 versus 50% non-carriers, p=0.085) or CRIB (53% gBRCA2 versus 43% non-carriers p=0.197) patterns. However, IDC histology was independently associated with bi-allelic BRCA2 alterations (OR 4.3, 95%CI 1.1-16.2) and PTEN homozygous…[Lees meer]
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McCann McPherson heeft een update geplaatst 1 week, 2 dagen geleden
UCA1 siRNA and overexpressed HOXA13 reversed the promotive effects of miR-185-5p inhibitor and inhibitory effects of miR-185-5p mimics on cell proliferation and metastasis, respectively.
The current findings reveal the important role of lncRNA UCA1/miR-185-5p/HOXA13 regulatory network in LSCC cells, and potentially provide new insights…[Lees meer]
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McCann McPherson heeft een update geplaatst 1 week, 3 dagen geleden
In addition, their roles and mechanisms in patients with HF with preserved ejection fraction or acute HF have also attracted attention. In this review article, we discuss the possible mechanisms and applications of SGLT2 inhibitors in HF.Background Screening echocardiograms can detect early-stage rheumatic heart disease (RHD), offering a chance to…[Lees meer]
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McCann McPherson heeft een update geplaatst 1 week, 5 dagen geleden
To analyze clinical and laboratory parameters, and treatment outcomes of children with autoimmune hemolytic anemia (AIHA).
Retrospective analysis of 50 children aged 0-18 years. Monospecific direct antiglobulin test (DAT) and investigations for secondary causes were performed. Disease status was categorized based on Cerevance…[Lees meer]
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McCann McPherson is geregistreerd lid geworden 1 week, 5 dagen geleden
