@waterverse05
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This DPPIV inhibitor was ineffective in βSENP1+/- or βSENP1- / – mice. Finally, we confirm impaired exocytotic responses of β-cells and reduced insulin secretion from islets of βSENP1- / – mice and show that the ability of Exendin 4 to enhance exocytosis is lost in these cells. Thus, an impaired ability of glucose to amplify insulin exo […] Bekijken