Chu Penn

This review analyzes the pathophysiology of postoperative nausea and vomiting (PONV), the current recommendations for PONV prevention, the pharmacokinetic and pharmacodynamic profile of aprepitant, and the supporting evidence for its efficacy in managing PONV, both as a single agent and in combination therapy.

Aprepitant’s deployment in the…[Lees meer]

Cannabinoid immunoassay and International Classification of Diseases code positivity exhibited a considerable surge in most states during legalization, yet the rates of positivity differed substantially. The existence of dispensaries in states with medical and/or recreational cannabis laws might affect the positive sentiment of the population. In…[Lees meer]

Optimal linezolid therapy should not be postponed to avoid the risk of serotonin syndrome arising. The data confirms a low rate of serotonin toxicity cases when linezolid is used in isolation or combined with other serotonergic medications.

In the interest of optimal patient care, linezolid therapy should not be postponed or delayed when…[Lees meer]

Through a combined effort, we pinpoint a pathway involving kindlin-2, Stat3, and Runx2 within articular chondrocytes, which is crucial for preserving articular cartilage health, suggesting a potential therapeutic approach for osteoarthritis.

Non-rhythmic, rapid, and repeatedly occurring movements or vocalizations are known as tics. While…[Lees meer]

For women aged 42-54 and 55, artificial tears infused with trehalose and hyaluronic acid substantially lessened the manifestations of dry eye disease (DED). The observed alleviation of symptoms was more marked in women aged 42 to 54, implying a more robust system for recovery from inflammatory responses and restoration of ocular surface…[Lees meer]