Daniels Travis

This paper reports PDE methodology in detail, from collection of patient samples through to endpoint analysis. It provides a detailed description of explant derivation and culture methods, highlighting bespoke conditions for particular tumors, where appropriate. read more For endpoint analysis, there is a focus on multiplexed immunofluorescence…[Lees meer]

Two commercial chimeric antigen receptor (CAR) T cell products, axicabtagene-ciloleucel (Yescarta®) and tisagenlecleucel (Kymriah®), are registered for the treatment of B cell neoplasia, for which an increased supply of CAR T cell products is required.

The production of patient-specific CAR T cells as advanced therapy medicinal products (…[Lees meer]

Little is known about the prevalence and impact on treatment of comorbid personality disorders for adults undertaking online cognitive behaviour therapy (internet-delivered or internet-based cognitive behaviour therapy (iCBT)) for anxiety and depressive disorders. This study explored how common comorbid personality difficulties were in a large…[Lees meer]

o correctly discriminate between TIR3A nodules in which a conservative approach may be used, and those in which additional test, such as molecular test, may be indicated. On the contrary, in TIR3B nodules both US risk stratification and seven-gene panel seem to be of little use, because the risk of thyroid cancer remains high regardless of US…[Lees meer]

uces the stress levels of caregivers, is effective in regulating blood pressure and pulse rate, does not cause a significant change on saliva cortisol level, and provides relief to caregivers.

Reiki reduces the stress levels of caregivers, is effective in regulating blood pressure and pulse rate, does not cause a significant change on saliva…[Lees meer]

To develop a sleep staging method from wrist-worn accelerometry and the photoplethysmogram (PPG) by leveraging transfer learning from a large electrocardiogram (ECG) database.

In previous work, we developed a deep convolutional neural network for sleep staging from ECG using the cross-spectrogram of ECG-derived respiration and…[Lees meer]

Investigations of the pubic ligaments might help to determine symphysis instability or severity of injury and should be included as a further criterion for surgical management.

The APL is the ligamentous anchor for the originating and inserting muscles. Investigations of the pubic ligaments might help to determine symphysis instability or…[Lees meer]

Mouse and human intrinsic clearance data highlighted the high metabolic stability of compounds 3 a, 3 d and 3 g. Further studies will be performed on the new compounds 3 a and 3 c to assess their anticancer potential in different cancer contexts. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.Elevated atmospheric CO2 (eCO2 ) generally…[Lees meer]

We show that multifocal 1064 nm Raman microscopy based on Hadamard-coded multifocal arrays is useful for imaging carbon nanotubes (CNTs) that would otherwise be damaged if a conventional single focus microscope design is used. The damage threshold for CNTs, dependent on laser power density and exposure time, limits the spectral detection…[Lees meer]