@santabrandy8
actief 10 uren, 7 minuten geleden
Based on the interaction modes of the natural 20S proteasome inhibitors TMC-95A, we have previously discovered a dipeptide 1. To explore the SAR around compound 1, we designed and synthesized a series of dipeptides (8-38) with a fragment-based strategy. Among them, nine compounds showed significant inhibitory activities against the […] Bekijken
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Coffey Vazquez heeft een update geplaatst 10 uren, 7 minuten geleden
Based on the interaction modes of the natural 20S proteasome inhibitors TMC-95A, we have previously discovered a dipeptide 1. To explore the SAR around compound 1, we designed and synthesized a series of dipeptides (8-38) with a fragment-based strategy. Among them, nine compounds showed significant inhibitory activities against the…[Lees meer]
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Coffey Vazquez is geregistreerd lid geworden 10 uren, 23 minuten geleden
