@gongrun0
actief 1 week, 2 dagen geleden-
Soto Mcfarland heeft een update geplaatst 2 weken, 2 dagen geleden
Described here is a Cu-catalyzed [2 + 2 + 1] modular synthesis of full-substituted β-pyrrolinones from simple amines, alkynes, and α-diazo-β-ketoesters. This approach involving the regioselective C-nucleophilic attack of enamines, uncommon C-nucleophilic addition to ketenes, and umpolung of imines enables the direct synthesis of fu…[Lees meer]
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Soto Mcfarland heeft een update geplaatst 2 weken, 4 dagen geleden
0% versus 1.3%, p=0.0068, 59k versus 12k*10
/l, p=0.0081) and at the moment of toxicity (5.2% versus 1.2%, p=0.0106 and 47k versus 16k*10
/l, p=0.0466). Baseline percentage NKT cells predicted pulmonary toxicity with 0.78 sensitivity and 1.0 specificity.
Our results suggest that baseline CD4+ effector cells may be predictive of…[Lees meer]
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Soto Mcfarland heeft een update geplaatst 2 weken, 5 dagen geleden
Mutations in NAIPs and NLRC4 are linked to autoinflammatory disorders in humans. In this review, we highlight the role of the NAIP/NLRC4 inflammasome in host defense, autoinflammatory diseases, cancer, and cell death. We also discuss evidence pointing to a role of NLRC4 in PANoptosis, which was recently identified as a unique inflammatory…[Lees meer]
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Soto Mcfarland is geregistreerd lid geworden 2 weken, 5 dagen geleden
