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Conversely, an increase in TRIM29 expression could initiate pyroptosis, a process mitigated by inhibiting NF-κB activity, suggesting that TRIM29 facilitates pyroptosis via the NF-κB signaling pathway. Mechanistic studies demonstrated the interaction between TRIM29 and IB, leading to the ubiquitination-dependent degradation of IB, a crucial s […] Bekijken
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