Kahn Aarup

Compared with the noncancerous tissues, the levels of TRPM8 in BCa tissues were significantly increased. Knockdown or inhibition of the activity of the TRPM8 protein in BCa cells reduced cell proliferation and migration. Moreover, the production of ROS was increased in cells treated with siTRPM8, which was accompanied by increased levels of…[Lees meer]

Aspects of the living environment can affect health and wellbeing of children and adolescents. Whereas most previous studies assessed the more distant residential urban environment, less is known on possible effects of the close environment. The present study investigated associations of the proportion of streets and green spaces in the immediate…[Lees meer]

Paris Agreement’s 1.5 °C or 2.0 °C global warming targets call for human concerns on warming climate on human society and environment in general. Here we analyzed spatiotemporal patterns and related impacts of precipitation extremes on human society across China using NEX-GDDP (NASA Earth Exchange Global Daily Downscaled Projections) dataset. We f…[Lees meer]

The volatile biomarkers of the alkanes and methylated alkanes are related to oxidative and lipid peroxidation of the cell membrane. The lung alveolar cell model has the potential to explore the volatile biomarkers of particulate-induced lung injury.We study the joint effect of the non-linearity of interactions and noise on coevolutionary dynamics.…[Lees meer]

Furthermore, imaged Cx26/Cx30-HA triple liganded by Fab-HA showed multiple arrangements that can be derived from the law of total probabilities. Atomic force microscopy imaging of ringlike structures of Cx26/Cx30-HA hemichannels confirmed these findings and also detected a polydisperse distribution of stoichiometries. Our results indicate a…[Lees meer]

The experimental data reported for those substances could indicate both autophagy activation and inhibition, requiring further investigation. Thus, the reviewed molecules were divided into two groups having validated and non-validated autophagy modulatory effects. This review gives an analysis of the recent updates in the field and raises an…[Lees meer]