Pike Upchurch

  • Pike Upchurch heeft een update geplaatst 6 uren, 19 minuten geleden

    Aims To evaluate the population pharmacokinetics (PopPK) of olanzapine in children and devise a model-informed pediatric dosing scheme. Method The PopPK of olanzapine was characterized using opportunistically collected plasma samples from children receiving olanzapine per standard of care for any indication. A nonlinear mixed effect modeling…[Lees meer]

  • Pike Upchurch heeft een update geplaatst 6 dagen, 5 uren geleden

    This review will define current knowledge of leukocyte metabolic dysfunction during and after sepsis and trauma. We will further discuss therapeutic strategies that target leukocyte mitochondrial function and might have value in preventing or reversing sepsis- and trauma-induced immune dysfunction.Cytokines are soluble factors that play vital…[Lees meer]

  • Pike Upchurch heeft een update geplaatst 1 week, 1 dag geleden

    Discussion The RAS/MAPK pathway plays an essential role in human development; hence, its dysregulation not surprisingly results in severe congenital anomalies, such as phenotypically overlapping syndromes termed RASopathies. To our best knowledge, we report here the first CNV causing haploinsufficiency of BRAF, resulting in dysregulation of the…[Lees meer]

  • Pike Upchurch heeft een update geplaatst 1 week, 2 dagen geleden

    riosis depends on medication. Additionally, the adequacy of the Rome criteria to differentiate IBS from the shared symptomatology of other diseases with visceral hypersensitivity must be further evaluated. OBJECTIVE Peritoneal adhesions may develop after every abdominopelvic surgery. Many agents and technical modifications have been investigated…[Lees meer]

  • Pike Upchurch is geregistreerd lid geworden 1 week, 2 dagen geleden

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