Spence Sears

  • Spence Sears heeft een update geplaatst 3 dagen, 6 uren geleden

    activation of ISO/β1-AR signal aggravated cardiac inflammatory infiltration, promoted CD11b+ myeloid cell mobilization, and enhanced CD11b+Ly6C+/low macrophage differentiation, which was further exacerbated by STAT6 deficiency. Furthermore, β1-AR mRNA expression significantly increased in splenic CD11b+ myeloid cells compared to their bone m…[Lees meer]

  • Spence Sears heeft een update geplaatst 4 dagen, 6 uren geleden

    eatest clinical effect was 0.4μg/ml, which is important because there may be no additional analgesic benefit of dexmedetomidine greater than 0.4μg/ml.

    In this study, the lowest concentration of dexmedetomidine in ropivacaine with the greatest clinical effect was 0.4 μg/ml, which is important because there may be no additional analgesic be…[Lees meer]

  • Spence Sears heeft een update geplaatst 5 dagen, 6 uren geleden

    We further demonstrated that STAT5A mediated SUMOylated PKM2-induced glycolysis and biological behaviors. Interestingly, GA treatment attenuated the severity of arthritis in mice with collagen-induced arthritis and human TNF-α transgenic mice. These findings suggest that an increase in synovial SAE1/UBA2 may contribute to synovial glycolysis and…[Lees meer]

  • Spence Sears heeft een update geplaatst 6 dagen, 6 uren geleden

    Recent economic and environmental literature suggests that the current state of energy use in South Africa amidst rapid growing population is unsustainable. Researchers in this area mostly focus on the effect of fossil energy use on carbon (CO2) emission, which represents only an aspect of environmental quality. In contrast, the current study…[Lees meer]

  • Spence Sears heeft een update geplaatst 1 week geleden

    The predictions confirmed that lunge affected the biomechanical behavior of ligaments. Displacement controlled finite element analysis of knee flexion can be simulated on the basis of fluoroscopic kinematic data to achieve physiologic movement. [Orthopedics. 2021;44(1)e61-e67.].The internet is increasingly used to access patient education…[Lees meer]

  • Spence Sears heeft een update geplaatst 1 week, 1 dag geleden

    77, 95% confidence interval (CI)=1.03-3.03]; (2) compared with full-time employment, unemployment was negatively associated with non-daily and daily e-cigarette use (RRR=0.38, 95% CI=0.18-0.81; RRR=0.12, 95% CI=0.02-0.56) and other economic inactivity was negatively associated with daily e-cigarette use (RRR=0.39, 95% CI =0.16-0.93).

    Among…[Lees meer]

  • Spence Sears heeft een update geplaatst 1 week, 2 dagen geleden

    In 154 (43%) of 357 episodes without microbiologically documented infection, uninterrupted postoperative antibiotic administration was continued for more than 3 days and in 80 (22%) for more than 5 days.

    The rate of postoperative bacterial or fungal infection at our institution is comparable to current literature. High surgical complexity…[Lees meer]

  • Spence Sears heeft een update geplaatst 1 week, 5 dagen geleden

    Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experimental endotoxin-induced pancreatic injury and aimed to identify LPS in human CP tissue. Pancreatic…[Lees meer]

  • Spence Sears heeft een update geplaatst 1 week, 5 dagen geleden

    Their potential to treat bacterial and fungal strains has been determined, and highlight complexes have selective growth inhibition of up to 87-100 % against Staphylococcus aureus and Candida albicans.

    Type-III selective intrauterine growth restriction (sIUGR) is associated with a high and unpredictable risk of fetal death and fetal brain i…[Lees meer]

  • Spence Sears is geregistreerd lid geworden 1 week, 5 dagen geleden

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